8.30-13.30 

            Registration & Satellite Symposia
 
14.00-16.00 

Chair: F. Tedesco (Italy), SS. Pierangeli (USA)

  
 

            aPL Targets and Mediated Effects

  
 

PL-binding Proteins

SA Krilis (beta2GPI)
 

T.Koike (PT)
 

Target Cells

R. Roubey (Mo)

 

PL Meroni (EC)
 

 Experimental in vivo models 

 M Blank (mimicry)

  
     SS Pierangeli (in vivo models)  
     J Rauch (SLE>APS)  
  10 min each talk + 10 min common discussion

 

Chair: V. Pengo (Italy), T. Koike (Japan)
 

3 selected presentations
10 min each talk + 5 min common discussion
16.00-16.15 

Coffee  break
16.15-17.30

Chair: S. Romagnani (Italy), N. Rose (USA)
 

            Round Table. Inflammatory events: YES or NOT?
     YES  

   F Tedesco (Italy)

  
   NO

   J Rand (USA)

  
  10 min each talk + 10 min common discussion

 

Chair: M. Galeazzi (Siena), P. Von Landerberg (Germany)
 

3 selected presentations
10 min each talk + 15 min common discussion
17.30-18.30 

Chair: G. Valesini (Italy), J. Salmon (USA)

            Round Table.  aPL and arterial events:  YES or NOT?
 

YES    M Khamashta
 

Arterial events in unselected patients series    P De Groot
  10 min each talk + 10 min common discussion
 

2 selected presentations
  10 min each talk + 10 min common discussion
18.30 

Chair: A. Tincani (Italy),  W.A.Wilson (USA)

            Genetic of APS
 

  What we know      M. Galeazzi (Italy)

 

  What we should know      M. Riquelme (Sweeden)
10 min each talk + 10 min common discussion

   2 selected presentations
10 min each talk + 10 min common discussion
19.30 

Opening Ceremony:
Welcome to Florence
  A. Passaleva
 
 

The APS story
Chairpersons: N. Harris, A. Tincani, PL.Meroni
                                                                      
7.00-8.00 

            Meet the professor
 
8.30-10.30 

Chair: S. Bombardieri (Italy), GRV Hughes (UK)

  
 

             Therapeutical Intervention

  
 

Tips and traps of keeping your patient's INR stable      R. Levy (Brasil)
 

When the standard regimen fails      JC.Piette (France)
 

Additional therapies       P. Youinou (France)
  10 min each talk + 10 min common discussion
   
 

Chair: L. Emmi (Italy), D. Erkan (USA)
 

5 selected presentations
  10 min each talk + 15 min common discussion
10.30-11.00 

Coffee  break and poster viewing
11.00-12.00 

Chair: T. Barbui (Italy), M. Petri (USA)

        Round Table.  Primary prophylaxis therapy: ALWAYS  or JUST IN SOME CASES?
 

  Always

  Ruitz Irastorza (Spain)

  In some cases

  D. Erkan (USA)
  10 min each talk + 10 min common discussion
 

2 selected presentations
10 min each talk + 10 min common discussion
12.00-14.00 

Lunch and poster viewing

 

Meeting of the International Committee: proposals for the next meetings

14.00-16.00 

Chair: PM. Mannucci (Italy),  RH Derksen (The Netherands)

            Non Traditional Clinical Manifestations:

 

New subset of APS       R Asherson (South Africa)

 

ADAMTS 13 deficiency as risk factor for thrombosis in APS      S Machin (UK)
 

CNS involvement          Y Shoenfeld (Israel)
 

Seronegative APS        G Valesini (Italy)
 

Kidney involvement     A Sinico (Italy)
  10 min each talk + 20 min common discussion
 

 
 

Chair: PL. Meroni (Italy), P. De Groot (The Netherlands)

 

4 selected presentations
10 min each talk + 10 min common discussion
16.00-16.15 

Coffee  break
16.15 -17.30 

Chair: M Galli (Italy), J.A. McIntyre(USA)

            Round Table: aPL detection assays: the real life in 2007  (including assay standardization)
 

 How the assays should be used? LA

V. Pengo (Italy)  

 How the assays should be used? Solid phase assays

G. Reber (Switzerland)
  10 min each talk + 10 min common discussion
 

 
 

Chair: A. Tincani (Italy), M. S. Marco (France)
 

3 selected presentations
10 min each talk + 10 min common discussion
17.30-18.30

Chair: A. Doria (Padova), MD Lockshin (USA)

          Round Table: Long follow up in aPL positive patients/subjects
 

  Long follow up

  The European aPL Forum R Cervera (Spain)

  Atherosclerosis

  M Petri (USA)
  10 min each talk + 10 min common discussion

2 selected presentations
  10 min each talk + 10 min common discussion
18.30-19.45 

Patients’ Session
20.00-20.30

APS: the widening spectrum
Lecture by GRV. Hughes (UK)

Chairman: A. Passaleva
Open to patients and participants
20.30

Social Dinner
 
AESKU INSTITUTE Prizes for the best selected presentations
M. Thorsten, A.Tincani, PL. Meroni, A. Passaleva
Announcement of the V International Conference on Sex Hormones,
Pregnancy and the Rheumatic Diseases
                                                                     
8.30-10.30  Chair: PL. Meroni (Italy), J. Rand (USA)  
 

Antiphospholipid damage to the foetus: from thrombosis to adaptive & innate   immune responses (pathogenic mechanisms)
 

Complement: the new player?      J. Salmon (USA)
 

Target cells: just fetal or maternal cells?     I. Cetin (Italy)
 

Heparin and ASA: should we reconsider their mechanism of action?    R. Rai (UK)
  10 min each talk + 10 min common discussion
   
 

Chair: Y. Shoenfeld (Israel), M. Costa (Italy)
 

6 selected presentations
  10 min each talk + 20 min common discussion
10.30-10.45 

Coffee  break
10.45-12.30 

Chair: I. Cetin (Italy), R Lahita (USA)

Pathogenesis of the antiphospholipid mediated pregnancy complications: infertility, miscarriage and preclampsia
 

Miscarriages versus fetal losses: different pathogenic mechanisms? W. Branch (USA)
 

Preeclampsia and HELLP: aPL-related pregnancy complications?   A. Lojacono (Italy)
 

Infertility: updating on the aPL role     A. Carp (Israel)
  10 min each talk + 10 min common discussion
 

 
 

Chair: A. Lojacono (Italy), W. Branch (USA)
 

4 selected presentations
10 min each talk + 15 min common discussion
12.30-14.00 

 Lunch and poster viewing
14.00-16.00 

Chair: F Falcini (Italy), L Regan (UK)

            Mothers and babies: long term outcome in APS syndrome
 

Patients with obstetrical APS only      A. Park (USA)

 

Children of patients with APS      MC. Boffa (France)

 

Neuropsychological development of children of aPL mothers     A. Tincani (Italy) 

  10 min each talk + 10 min common discussion
 

 
 

Chair: G. R. Cimaz (France), Mc Carty (USA)
 

5 selected presentations
10 min each talk + 20 min common discussion
16.00-16.15 

 Coffee  break
16.15-17.30 

Chair: Chair: G Mello (Italy), W Branch (USA)

            Treating difficult cases
 

Treatment of pregnant patients not fulfilling the classification criteria   W. Ossola (Italy)

 

Treatment of pregnant patients with previous thrombosis    RH Derksen (The Netherands)
 

Contraception in APS and aPL positive women     Sancez Guerriero (Mexico) 

 

Answers to frequently unanswered questions     M Lockshin (USA) & A.Tincani (Italy)
  10 min each talk + 15 min common discussion
17.30-18.30

 

 
Chairpersons: CUTOLO M,  MATUCCI M
with the participation of local Authorities
Introductory Lecture by MD.  Lockshin - USA

       Pagine in Italiano

 

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12th International Congress on Antiphospholipid Antibodies
Florence, April 18-20 2007